DETAILS, FICTION AND PHENOBARBITAL MAINTENANCE DOSE IN NEONATES

After stopping a CYP3A4 inducer, as the effects on the inducer decline, the fentanyl plasma concentration will raise which could maximize or prolong equally the therapeutic and adverse effects.Major - Use Alternative (1)fentanyl and phenobarbital equally maximize sedation. Prevent or Use Alternate Drug. Limit use to patients for whom alternative tr